The demand for new workers in STEM (science, technology, engineering and mathematics) occupations in Arizona is a function of net job growth in these occupations in the state and the number of workers leaving STEM jobs in Arizona. Employees may leave their position for various reasons, including to retire, to move out of the state, or to change their profession. The supply of new workers in STEM occupations in Arizona is a function of the number of new college graduates in related majors, the number of workers moving to the state who are qualified to fill STEM jobs, and the number of Arizonans who are qualified to fill STEM jobs moving from a non-STEM to STEM occupation.

The attraction of a federal research laboratory to Arizona as a strategic economic development initiative of the Arizona Economic Resource Organization can be justified based on the literature cited below, the relationship of federally funded research and development centers to broader measures of research and development and prosperity, and the implementation of this strategy elsewhere. A primary objective of attracting a federal research facility is to help create a climate that is conducive to private-sector economic development, especially related to research and development. On a purely cost-benefit basis, the pursuit of a federal lab has strong appeal since the benefits largely will accrue within Arizona while a considerable portion of the costs conceivably will be borne by the federal government.